We went through multiple trial and errors when choosing a blockchain for our projects, in the last several years.
We went through evaluating use of - ethereum, avalanche, binance smart chain, polygon.
By their nature blockchains are ‘rent seeking’ entities and we did not want to pay rent to other blockchain for our transactions.
Currently, in our ‘Decentralized web’ project we use our owned / independent blockchain instance, visible on -
https://decentralizeweb.org/dw_chain.php